Clinical Studies About Collagen's Effectiveness
Anti-Ageing
To date, several controlled clinical studies have been performed proving the efficacy and benefits of collagen peptides on skin properties such as hydration, elasticity and reduction of wrinkles and recently a number of therapeutic formulations of hydrolysed collagen have been developed for treatment of skin ageing.
These fall into the category of nutraceuticals- products inferring real benefits to all those with ageing skin.
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Skin Health
Skin dryness and an accelerated fragmentation of the collagen network in the dermis are hallmarks of skin aging.
Nutrition is a key factor influencing skin health and consequently its appearance.
A wide range of dietary supplements is offered to improve skin health.
Collagen peptides are used as a bioactive ingredient shown in pre-clinical studies to improve skin barrier function, to induce the synthesis of collagen and hyaluronic acid, and to promote fibroblast growth and migration.
Bone Health
Hydrolyzed collagen improves bone metabolism and biomechanical parameters in ovariectomized mice: An in vitro and in vivo study.
It is concluded that dietary hydrolyzed collagen increases osteoblast activity (as measured in primary tissue culture), which acts on bone remodeling and increases the external diameter of cortical areas of the femurs.
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Osteroarthiritis Prevention
Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or regenerative capability represent a critical unmet need.
Recently, oral consumption of a hydrolyzed type 1 collagen (hCol1) preparation has been reported to reduce pain in human OA and support a positive influence on chondrocyte function.
Osteoporosis Prevention
Osteoporosis is a chronic and asymptomatic disease characterized by low bone mass and skeletal grmicroarchitectural deterioration, increased risk of fracture and associated co-morbidities most prevalent in the elderly.
A growing body of evidence demonstrates that Hydrolyzed Collagen’s bio active properties beneficial for bone tissue, including stimulation of bone forming cells, improvement of calcium absorption, anti-inflammatory and antioxidant capacities.
Those properties render HC a new and innovative candidate for putative dietary intervention in the prevention of osteoporosis.
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